详细描述:
磷酸化的EGFR (Tyr1045)的抗体仅在Tyr1045位点被磷酸化后才能检测到内源EGFR的水平。本抗体可能与激活的EGFR家族的其它蛋白(如ErbB2)发生交叉反应。多克隆抗体通过用合成多肽免疫动物得到,该磷酸化多肽是根据人的EGFR蛋白Tyr1045附近的氨基酸序列合成的。抗体经过protein A和亲和层析纯化。Phospho-EGF Receptor (Tyr1045) Antibody detects EGF receptor only when phosphorylated at tyrosine1045. The antibody may cross-react with other activated EGF receptor family members (e.g. ErbB2). Polyclonal antibodies are produced by immunizing animals with a synthetic phosphopeptide corresponding to residues surrounding Tyr1045 of human EGF receptor. Antibodies are purified by protein A and peptide affinity chromatography.